Material Detail

This video was recorded at 23rd Annual Conference on Neural Information Processing Systems (NIPS), Vancouver 2009. Interventions in infectious diseases are increasingly relying on computational biology and genomic methods. Estimating changes in viral genetic diversity in a population could be a new potential method to evaluate vaccination strategies in populations. Transgenic mosquitoes immune to a pathogen are being developed to replace the native mosquito vector of a number of vector-borne diseases. High throughput methods are being used to elucidate mechanisms of immune memory with the promise of developing better vaccines. Large-scale computer simulation models are useful for exploring interventions and could benefit from input from network and graph theory. In this talk, we discuss a few novel applications of computational biology in understanding infectious diseases and interventions.

Disciplines:

• Science and Technology  / Computer Science