Material Detail

A lesson that requires students to work through a series of questions pertaining to the genetics of sickle cell disease and its relationship to malaria. These questions will probe students' understanding of Mendelian genetics, probability, pedigree analysis, and chi-square statistics. Appropriate for: high school biology (all levels), introductory college biology. This classroom activity uses the information presented in the short film The Making of the Fittest: Natural Selection in Humans to take students through a series of questions pertaining to the genetics of sickle cell disease and its relationship to malaria resistance. The questions are divided into sections: Mendelian Genetics and Probability, Pedigrees, and Chi-Square Statistics. Within each section, the questions sequentially move from a basic level to a more advanced level in order to develop the skills of the students.

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