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The adrenergic system in cardiovascular physiology and pathophysiology

The adrenergic system in cardiovascular physiology and pathophysiology

Cardiovascular diseases pose an enormous clinical challenge, remaining the most common cause of death in the world. β-adrenoceptors play an important role on cardiac, vascular and/or endothelial function at a cellular level with relevant applications in several cardiovascular diseases, such as heart failure and hypertension. G protein–coupled receptors (GPCRs), including β-adrenergic receptors, constitute the most ubiquitous superfamily of...

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