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Exploring the Metabolic and Genetic Control of Gene Expression on a Genomic Scale

Exploring the Metabolic and Genetic Control of Gene Expression on a Genomic Scale

DNA microarrays containing virtually every gene ofSaccharomyces cerevisiae were used to carry out a comprehensive investigation of the temporal program of gene expression accompanying the metabolic shift from fermentation to respiration. The expression profiles observed for genes with known metabolic functions pointed to features of the metabolic reprogramming that occur during the diauxic shift, and the expression patterns of many previously...

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