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Children's Hospital Boston: Hodgkin's Lymphoma
Hodgkin's lymphoma is a type of cancer in the lymphatic system. Hodgkin's lymphoma causes the cells in the lymphatic system to abnormally reproduce, eventually making the body less able to fight infection and cause swelling in the lymph nodes. Hodgkin's disease is distinguished from other types of lymphomas by the presence of a particular type of diseased cell, called the Reed-Sternberg cell. Another way physicians identify Hodgkin's disease is by the way it progresses. Hodgkin's disease usually begins in the lymph nodes of one part of the body, usually in the head, neck or chest. It then tends to spread in a predictable manner from one part of the lymph system to the next, and, in advanced stages, to the lungs, liver, bone marrow, bones, or other organs. The several subtypes of Hodgkin's lymphoma are nodular sclerosing, lymphocyte depleted, lymphocyte predominant, and mixed cellularity.
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