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Toxicity/Sepsis- Signs and Symptoms Sepsis is a systemic response to inflammation as a result of uncontrolled infection. There is also a release of cytokines which lead to further inflammation and vascular dilation. Blood is shunted from the essential organs to non essential organs (the skin) leading to increased body temperature (along with response to infection). The heart begins to beat faster in response to the infection and to the decreased cardiac output as a result of the massive vasodilation.

The 6 T's:

Tachycardia

Tachypnea

Tremors

Toxic look

Tiredness

Temperature (fever)

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